Set three years after the events of Uncharted 3: Drake’s Deception, Nathan Drake, now retired as a fortune hunter, has settled into a normal life. His world is turned upside-down when his older brother Sam, long believed dead, suddenly appears seeking Drake’s help. Together they embark on a globe-trotting journey in pursuit of a conspiracy behind a long lost pirate colony and its fabled pirate treasure. Naughty Dog outlined the game’s plot as “his greatest adventure yet and will test his physical limits, his resolve, and ultimately what he’s willing to sacrifice to save the ones he loves.